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AlphaLISA SureFire Ultra Human and Mouse Total BCL-XL Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human and Mouse Total BCL-XL assay is a sandwich immunoassay for quantitative detection of total BCL-XL in cellular lysates using Alpha Technology.

Part Number: ALSU-TBCLXL-A500
Unit Size:
Part Number: ALSU-TBCLXL-A10K
Unit Size:
Part Number: ALSU-TBCLXL-A50K
Unit Size:
Part Number: ALSU-TBCLXL-A-HV
Unit Size:
  • B-cell lymphoma-extra large (BCL-XL) is a member of the BCL-2 protein family resulting in apoptosis inhibition or pro-survival function. Beclin 1, a key factor in autophagy regulation, interacts with BCL-XL. BCL-XL is also essential for the survival of neurons and is involved in protective roles in neuronal injuries. Numerous cancers and other diseases are associated with BCL-XL, including acute lymphoblastic leukemia, non-Hodgkin’s lymphoma, small cell lung cancer, breast cancer, gastric cancer, prostate cancer, and neurodegenerative disorders.

    The AlphaLISA SureFire Human and Mouse Total BCL-XL Detection Kit is a sandwich immunoassay for the quantitative detection of total BCL-XL in cellular lysates, using Alpha Technology.

    Formats:
    • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
    • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
    • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
    • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
    AlphaLISA SureFire Ultra kits are compatible with:
    • Cell and tissue lysates
    • Antibody modulators
    • Biotherapeutic antibodies
    Alpha SureFire kits can be used for:
    • Cellular kinase assays
    • Receptor activation studies
    • Screening

    For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

  • Application
    Protein Analysis & Detection
    Protein Detection
    Assay Target Class
    Phospho-protein
    Assay Technology
    Alpha
    Automation Compatible
    Yes
    Brand
    AlphaLISA SureFire Ultra
    Detection Method
    Alpha
    Experimental Type
    In vitro
    Target Species
    Human
    Mouse
    Therapeutic Area
    Neuroscience
    Oncology