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AlphaLISA SureFire Ultra Human Phospho-ATM (Ser1981) Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human Phospho-ATM (Ser1981) assay is a sandwich immunoassay for quantitative detection of phospho-ATM (Ser1981) in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Product Variants
Part number: ALSU-PATM-A500
Unit Size: 500 Assay Points
List price: USD 2,319.00
Your price:
USD 2,319.00
USD 2,319.00 /each
Part number: ALSU-PATM-A10K
Unit Size: 10,000 Assay Points
List price: USD 14,270.00
Your price:
USD 0.00
USD 14,270.00 /each
Part number: ALSU-PATM-A50K
Unit Size: 50,000 Assay Points
List price: USD 40,710.00
Your price:
USD 0.00
USD 40,710.00 /each
Part number: ALSU-PATM-A-HV
Unit Size: 100 Assay Points
List price: USD 803.53
Your price:
USD 0.00
USD 803.53 /each

Overview

Ataxia-telangiectasia mutated (ATM) is a protein belonging to the P13/P14-kinase family. ATM is an important cell cycle checkpoint kinase and functions to regulate a wide variety of downstream proteins including p53, BRCA1, CHK2, RAD17, RAD9, and NBS1. ATM also plays a key role in double stranded DNA breaks and responds by phosphorylating histone H2AX, thus initiating a complex involving various other proteins that are recruited to the damage site. ATM mutations are associated with neurodegenerative disease and cancer.

The AlphaLISA SureFire Ultra Human Phospho-ATM (Ser1981) assay is a sandwich immunoassay for the quantitative detection of phospho-ATM (Ser1981) in cellular lysates, using Alpha Technology.

Formats:
  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with:
  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies
Alpha SureFire kits can be used for:
  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Protein Analysis & Detection
Protein Detection
Assay Target Class
Phospho-protein
Assay Technology
Alpha
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Method
Alpha
Experimental Type
In vitro
Target Species
Human
Therapeutic Area
Central Nervous System
Oncology
Unit Size
500 Assay Points

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