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The AlphaLISA® SureFire® Ultra™ Human and Mouse Phospho-α-Synuclein (Ser129) assay is a sandwich immunoassay for quantitative detection of phospho-α-Synuclein (Ser129) in cellular lysates using Alpha Technology.
α-Synuclein is a neuronal protein encoded by the SNCA gene that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. α-Synuclein is a prominent component of intracellular fibrillary aggregates in the brains of patients suffering from synucleinopathies. This protein represents a key molecular hallmark for Parkinson’s disease, dementia with Lewy bodies, or multiple system atrophy. The extensive phosphorylation of α-Synuclein on Ser129 is also associated with a pathological event.
The AlphaLISA SureFire Human and Mouse Phospho-α-Synuclein (Ser129) Detection Kit is a sandwich immunoassay for the quantitative detection of phosphorylated alpha synuclein in cellular lysates, using Alpha Technology.
AlphaLISA SureFire Ultra