Our Membrane Target Systems: Serotonin 5HT-5A (human) membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
For research use only. Not for use in diagnostic procedures.
Membrane Target Systems are quality assured frozen membranes from cells that express Serotonin 5-HT5A (human) recombinant or endogenous receptors. We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPgS data is also provided for some of our Gi coupled receptors.
Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximity methods, such as FlashPlate, or classical filtration methods). Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined bycompetition binding assay (filtration). A complete product description and recommended protocol are included on the Certificate of Analysis.
Some of our receptors may be restricted for sale in specifiedcountries. Please inquire.
Concentration |
6 µg/µL protein
|
---|---|
Volume |
1000.0 µL
|
Application |
Drug Discovery & Development
|
---|---|
Assay Validation |
Binding
|
Assay Target Class |
GPCR
|
Brand |
Membrane Target Systems
|
Buffer |
50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
|
G-Alpha Natural Receptor |
Gi/Go
|
Host |
CHO-K1
|
Product Group |
Membrane Preparation
|
Receptor Type |
5-Hydroxytryptamine (Serotonin)
|
Species |
Human
|
Shipping Conditions |
Shipped in Dry Ice
|
Therapeutic Area |
Central Nervous System
Inflammation
|
Unit Size |
400 units
|
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