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Membrane Target Systems: Serotonin 5HT-5A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target Systems: Serotonin 5HT-5A (human) membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

For research use only. Not for use in diagnostic procedures.

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Part number: ES-401-M400UA
Unit Size: 400 units
List price: USD 2,769.00
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USD 2,769.00
USD 2,769.00 /each

Overview

Membrane Target Systems are quality assured frozen membranes from cells that express Serotonin 5-HT5A (human) recombinant or endogenous receptors. We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPgS data is also provided for some of our Gi coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximity methods, such as FlashPlate, or classical filtration methods). Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined bycompetition binding assay (filtration). A complete product description and recommended protocol are included on the Certificate of Analysis.

Some of our receptors may be restricted for sale in specifiedcountries. Please inquire.

Specifications

Concentration
6 µg/µL protein
Volume
1000.0 µL
Application
Drug Discovery & Development
Assay Validation
Binding
Assay Target Class
GPCR
Brand
Membrane Target Systems
Buffer
50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
G-Alpha Natural Receptor
Gi/Go
Host
CHO-K1
Product Group
Membrane Preparation
Receptor Type
5-Hydroxytryptamine (Serotonin)
Species
Human
Shipping Conditions
Shipped in Dry Ice
Therapeutic Area
Central Nervous System
Inflammation
Unit Size
400 units

Resources

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Radioligand selection guide

Discover a comprehensive collection of GPCR cell lines, membrane preparations, and complementary radioligands designed to drive...

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