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Oxytocin, [Tyrosyl-3,5-3H]-, 50µCi (1.85MBq)

Oxytocin, tritiated on the tyrosyl group. Oxytocin is a neurotransmitter that binds and activates oxytocin receptors.

For research use only. Not for use in diagnostic procedures.

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YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Feature Specification
Concentration 1 mCi/ml
Label Position Specifically Labeled
Molecular Weight 1007.23
Receptor Oxytocin

Oxytocin, tritiated on the tyrosyl group. Oxytocin is a neurotransmitter that binds and activates oxytocin receptors.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variant
Unit Size: 50 µCi
Part #:
NET858050UC
List Price
USD 4,216.00

Overview

Oxytocin is the endogenous ligand for oxytocin receptors. These receptors are a family of GPCRs that are involved in uterine contractions, milk production, stress, anxiety, social memory and recognition, and bonding.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET858:

  1. Braida, D., Donzelli, A., Martucci, R. et al. Neurohypophyseal hormones manipulation modulate social and anxiety-related behavior in zebrafish. Psychopharmacology (2012) 220: 319.
  2. Gimpl, G., Fahrenholz, F. Cholesterol as stabilizer of the oxytocin receptor, In Biochimica et Biophysica Acta (BBA) - Biomembranes (2002) 1564 (2): 384-392.

Specifications

Concentration
1 mCi/ml
Molecular Weight
1007.23
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Ethanol : water (8:2)
Detection Modality
Radiometric
Label Position
Specifically Labeled
Packaging
NENSure vial
Radioisotope
3H
Receptor
Oxytocin
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-20°C
Therapeutic Area
Gastrointestinal
Metabolic Disorders
Unit Size
50 µCi

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