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Membrane Target Systems: Melatonin MT2 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target Systems: Melatonin MT2 (human) membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.

For research use only. Not for use in diagnostic procedures

Part number: ES-621-M400UA
List price: USD 2,537.00
Your price:
USD 2,537.00
USD 2,537.00 /each

Overview

Membrane Target Systems are quality assured frozen membranes from cells that express Melatonin MT2 (human) recombinant or endogenous receptors. We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPgS data is also provided for some of our Gi coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximity methods, such as FlashPlate, or classical filtration methods).

Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet (see Certificate of Analysis).

Specifications

Application
Drug Discovery & Development
Assay Validation
Binding
Assay Target Class
GPCR
Assay Target Type
Membrane preparation
Brand
Membrane Target Systems
Host
CHO-K1
Receptor Type
Melatonin
Shipping Conditions
Shipped in Dry Ice
Unit Size
400 units

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Radioligand selection guide

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