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Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1-14C]-, 250 µCi (9.25 MBq)

5-Hydroxytryptamine Binoxalate (Serotonin Binoxalate), labeled with C-14 at the 1-position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors. NEC855 replaces product NEC225, which was labeled at the 2-position.

For research use only. Not for use in diagnostic procedures
Part Number: NEC855050UC
Unit Size: 50 µCi
Part Number: NEC855250UC
Unit Size: 250 µCi
  • 250 µCi quantity of 5-Hydroxytryptamine (5-HT) which binds and activates 5-HT (serotonin) receptors. These receptors are a group of GPCR and ligand-gated ion channels found in the peripheral and central nervous system, and are involved in anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation.

    We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

    Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

  • Brand
    NEN Radiochemicals
    Detection Method
    Radiometric
    Label Position
    Specifically Labeled
    Radioisotope
    C-14
    Receptor Type
    5-Hydroxytryptamine
    Special Ordering Information
    This is a radioactive product - shipping address must have a license to receive radioactive materials.
    Therapeutic Area
    Cardiovascular
    CNS & Neurologic
    Unit Size
    250 µCi

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Carbon-14 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Carbon-14. While we...