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Membrane Target Systems: Serotonin 5HT2c (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human serotonin 5HT2c receptor, 400 units.

For research use only. Not for use in diagnostic procedures

Part number: 6110548400UA
List price: USD 1,459.00
Your price:
USD 1,459.00
USD 1,459.00 /each

Overview

Membrane Target Systems are quality assured frozen membranes from cells that express Serotonin 5HT2c (human) recombinant or endogenous receptors.

We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTP?S data is also provided for some of our Gi-coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).

Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.

Some of our receptors may be restricted for sale in specified countries. Please inquire.

Specifications

Assay Validation
Binding
Assay Target Class
GPCR
Assay Target Type
Membrane preparation
Brand
Membrane Target Systems
G-Alpha Natural Receptor
Gq/G11
Host
HEK293
Receptor Type
5-Hydroxytryptamine (Serotonin)
Species
Human
Shipping Conditions
Shipped in Dry Ice
Therapeutic Area
Central Nervous System
Unit Size
400 units

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Radioligand selection guide

Discover a comprehensive collection of GPCR cell lines, membrane preparations, and complementary radioligands designed to drive...

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