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Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.
Membrane Target Systems are quality assured frozen membranes from cells that express Neurokinin NK1 (human) recombinant or endogenous receptors.
We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTP?S data is also provided for some of our Gi-coupled receptors.
Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).
Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.
Some of our receptors may be restricted for sale in specified countries. Please inquire.
Drug Discovery & Development
|Assay Target Class
|Assay Target Type
|G-Alpha Natural Receptor
Central Nervous System
Membrane Target Systems