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Membrane Target Systems: Neurokinin NK1 (human endogenous) membrane preparation, in UC11 cells. 400 Units.

Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.

For research use only. Not for use in diagnostic procedures
Part Number: 6110551400UA
Part Number: 6110551400UA
  • Membrane Target Systems are quality assured frozen membranes from cells that express Neurokinin NK1 (human) recombinant or endogenous receptors.

    We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTP?S data is also provided for some of our Gi-coupled receptors.

    Membranes are carefully prepared and ready for a variety of HTS applications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).

    Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.

    Some of our receptors may be restricted for sale in specified countries. Please inquire.

  • Application
    Drug Discovery & Development
    Assay Target Class
    GPCR
    Assay Target Type
    Membrane preparation
    G-Alpha Natural Receptor
    Gq/G11
    Host
    UC11
    Receptor Type
    Tachykinin
    Species
    Human
    Therapeutic Area
    Cardiovascular
    Central Nervous System
    Gastrointestinal
    Assay Validation
    Binding
    Brand
    Membrane Target Systems
    Unit Size
    400 units