Stable, recombinant AequoScreen® cell line expressing aequorin and the Serotonin receptor 5-HT2C, human recombinant in CHO-K1 host cells.
For research use only. Not for use in diagnostic procedures. Cell Line Terms and Conditions must be accepted before orders are placed. Additional agreement needed for commercial use. Click here.
Revvity's AequoScreen double transfected cell lines are provided in two vials of frozen cells, each containing ∽2.5 x 106 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available each cell line.
AequoScreen technology is a generic GPCR technology that can be used with Gs, Gi, and Gq-coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of resulting flash luminescence signal.
Features:
Revvity’s AequoScreen cell lines require accepted cell line Terms and Conditions prior to order processing. Additional agreement needed for commercial use. Please use link above to accept Terms and Conditions or to request an agreement for commercial use.
Application |
Drug Discovery & Development
|
---|---|
Brand |
AequoScreen
|
G-Alpha Coupling Protein |
Ga16
|
G-Alpha Natural Receptor |
Gq/G11
|
Host Cell Line |
CHO-K1
|
Host Species |
Human
|
Product Group |
Cell Line
|
Receptor |
5-Hydroxytryptamine (Serotonin)
|
Second Messenger Release |
Calcium flux
|
Shipping Conditions |
Shipped in Dry Ice
|
Special Ordering Information |
Requires accepted Terms and Conditions. Additional agreement needed for commercial use.
|
Target Class |
GPCR
|
Therapeutic Area |
Cardiovascular
Central Nervous System
Gastrointestinal
Metabolic
|
Unit Size |
5 million cells
|
Validation |
Binding
Calcium Fluorescence
Calcium Luminescence
|
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