Our Membrane Target Systems: Dopamine D3 (human) membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
For research use only. Not for use in diagnostic procedures.
Membrane Target Systems are quality assured frozen membranes from cells that express Dopamine D3 (human) recombinant or endogenous receptors.
We submit every batch of receptor to stringent quality controltesting that includes saturation radioligand binding assay todetermine receptor concentration (Bmax) and affinity (Kd).Competition binding assays are performed determine affinity (Ki)against known reference agonists and antagonists. GTPgS data isalso provided for some of our Gi coupled receptors.
Membranes are carefully prepared and ready for a variety of HTSapplications, including radioligand binding (using either proximitymethods, such as FlashPlate, or classical filtrationmethods).
Products are packaged as frozen crude membrane preparations. Oneassay unit is defined as micrograms of protein, defined bycompetition binding assay (filtration). A complete productdescription and recommended protocol are included on the ProductInformation Sheet
Some of our receptors may be restricted for sale in specifiedcountries. Please inquire.
Concentration |
1 µg/µL protein
|
---|---|
Volume |
400.0 µL
|
Application |
Drug Discovery & Development
|
---|---|
Assay Validation |
Binding
GTPγS
|
Assay Target Class |
GPCR
|
Brand |
Membrane Target Systems
|
Buffer |
50 mM Tris-HCL (pH 7.4), 0.5mM EDTA, 10mM MgCl2, 10% sucrose
|
G-Alpha Natural Receptor |
Gi/Go
|
Host |
CHO-K1
|
Product Group |
Membrane Preparation
|
Receptor Type |
Dopamine
|
Second Messenger Release |
GTP exchange
|
Species |
Human
|
Shipping Conditions |
Shipped in Dry Ice
|
Therapeutic Area |
Central Nervous System
|
Unit Size |
400 units
|
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