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N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 250 µCi

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

For research use only. Not for use in diagnostic procedures

Product Variants
Part number: NEX120250UC
Unit Size: 250 µCi
List price: USD 1,087.00
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USD 1,087.00
USD 1,087.00 /each
Part number: NEX120001MC
Unit Size: 1 mCi
List price: USD 1,811.00
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USD 0.00
USD 1,811.00 /each
Part number: NEX120002MC
Unit Size: 2 mCi
List price: USD 2,911.00
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USD 0.00
USD 2,911.00 /each

Overview

Iodination of proteins is a common method of adding a tracer with high specific activity to your protein of interest. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative methods. Bolton-Hunter reagent can be used to label peptides and proteins containing lysine residues. Available in 250 µCi size.

Specifications

Molecular Weight
387.2
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Detection Method
Radiometric
Fresh Lot Days
Fresh Upon Request
Label Position
Nominally Labeled
One Unit Contains
250.0 µCi
Radioisotope
125I
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size
250 µCi

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