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N-succinimidyl-3-(4-hydroxy-3-[125I]iodophenyl)propionate, Bolton-Hunter Reagent, 2 mCi

Bolton-Hunter reagent, monoiodinated. This product is used to iodinate proteins that do not contain tyrosine residues. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative labeling methods. An anhydrous benzene A charcoal trap is provided with each vial.

For research use only. Not for use in diagnostic procedures
Part Number: NEX120250UC
Unit Size: 250 µCi
Part Number: NEX120001MC
Unit Size: 1 mCi
Part Number: NEX120002MC
Unit Size: 2 mCi
  • Iodination of proteins is a common method of adding a tracer with high specific activity to your protein of interest. Bolton-Hunter reagent is the N-hydroxysuccinimide ester of iodinated p-hydroxyphenylpropionic acid. The active ester acylates terminal amino groups with the iodinated p-hydxyphenylpropionic residue, effectively introducing radioactive iodine into proteins and peptides. A non-oxidative technique, it is less harsh to proteins than alternative methods. Bolton-Hunter reagent can be used to label peptides and proteins containing lysine residues. Available in 2 mCi size.

  • Molecular Weight
    387.2
    Application
    Drug Discovery & Development
    Brand
    NEN Radiochemicals
    Detection Method
    Radiometric
    Fresh Lot Days
    Fresh Upon Request
    Label Position
    Nominally Labeled
    Radionuclide
    125I
    Radioisotope
    I-125
    Shipping Conditions
    Shipped Ambient
    Special Ordering Information
    This is a radioactive product - shipping address must have a license to receive radioactive materials.
    Unit Size
    2 mCi

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