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Angiotensin I (human), [125I]Tyr4-, 10 µCi (370 kBq), Species Activity: 2200 Ci/mmol (81.4TBq/mmol)
Angiotensin I (human), [125I]Tyr4-, 10 µCi (370 kBq), Species Activity: 2200 Ci/mmol (81.4TBq/mmol)
Angiotensin I, labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin I is the precursor to Angiotensin II, which a peptide hormone that causes vasoconstriction and increased blood pressure, and is a potential drug target for blood pressure regulation.
For research use only. Not for use in diagnostic procedures.
| Feature | Specification |
|---|---|
| Fresh Lot Days | First Monday of each month |
| Label Position | Nominally Labeled |
| Molecular Weight | ~1420 |
| Receptor | Angiotensin |
Angiotensin I, labeled with 125I on the tyrosine (Tyr4) residue. Angiotensin I is the precursor to Angiotensin II, which a peptide hormone that causes vasoconstriction and increased blood pressure, and is a potential drug target for blood pressure regulation.
For research use only. Not for use in diagnostic procedures.
Angiotensin I (human), [125I]Tyr4-, 10 µCi (370 kBq), Species Activity: 2200 Ci/mmol (81.4TBq/mmol)
Angiotensin I (human), [125I]Tyr4-, 10 µCi (370 kBq), Species Activity: 2200 Ci/mmol (81.4TBq/mmol)
Product information
Overview
10 µCi quantities of Angiotensin I (human), [125I]Tyr4-are available for your research.
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX101:
- Aurell, M., Pettersson, M., Berglund, G. Renin-Angiotensin System in Essential Hypertension. The Lancet, Volume 306, Issue 7930, 1975, Pages 342-345.
Specifications
| Molecular Weight |
~1420
|
|---|---|
| Specific Activity |
2200.0 Ci/mmol
|
| Application |
Drug Discovery & Development
|
|---|---|
| Brand |
NEN Radiochemicals
|
| Buffer/Solvent |
Lyophilized
|
| Detection Modality |
Radiometric
|
| Fresh Lot Days |
First Monday of each month
|
| Label Position |
Nominally Labeled
|
| Packaging |
NENSure vial
|
| Radioisotope |
125I
|
| Receptor |
Angiotensin
|
| Shipping Conditions |
Shipped Ambient
|
| Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
| Storage Conditions |
4°C
|
| Therapeutic Area |
Angiogenesis
Cardiovascular
|
| Unit Size |
10 µCi
|
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