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α-MSH, Nle4, D-Phe7, [125I], 10µCi

α-Melanocyte-stimulating hormone (α-MSH), labeled with 125I. α-MSH is an endogenous hormone that acts as a non-selective full agonist of melanocortin receptors MC1, MC3, MC4, and MC5.

For research use only. Not for use in diagnostic procedures

Product Variants
Part number: NEX352010UC
Unit Size: 10 µCi
List price: USD 1,863.00
Your price:
USD 1,863.00
USD 1,863.00 /each
Part number: NEX352050UC
Unit Size: 50 µCi
List price: USD 4,497.00
Your price:
USD 0.00
USD 4,497.00 /each


10 µCiQuantities of α-MSH, Nle4, D-Phe7, [125I] are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX352:

  1. Conde-Frieboes, K., Thøgersen, H., Lau, J.F., Sensfuss, U., Hansen, T.K., Christensen, L., Spetzler, J., Olsen, H.B., Nilsson, C., Raun, K., Dahl, K., Hansen, B.S., Wulff, B.S. (2012), Identification and in vivo and in vitro characterization of long acting and melanocortin 4 receptor (MC4-R) selective α-melanocyte-stimulating hormone (α-MSH) analogues. J Med Chem, 55 (5): 1969-1977.
  2. Vagner, J., Handl, H.L., Gillies, R.J., Hruby, V.J. (2004), Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of alpha-MSH. Bioorg Med Chem Lett, 14 (1): 211-215.


Drug Discovery & Development
NEN Radiochemicals
Detection Method
Fresh Lot Days
Third Monday of each month
Label Position
Nominally Labeled
Receptor Type
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area
CNS & Neurologic
Metabolic Disorders
Unit Size
10 µCi


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Iodine-125 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Iodine-125. While we...

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