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Protein Clear HR LabChip Touch 24
The Protein Clear HR LabChip Touch chip is used with the LabChip® GXII Touch Protein Clear™ HR assay on the LabChip® GXII Touch™ instrument. The LabChip GXII Touch Protein Clear HR assay is designed for the high-resolution protein purity assessment of monoclonal antibodies (mAb) within research and development, enabling the detection and visualization of impurities within a sample, down to 5 ng/μL.
Product information
Overview
Protein Impurity Analysis in seconds
The Protein Clear HR LabChip Touch 24 runs 48 or fewer sample batch sizes per prime on the LabChip GXII Touch 24 instrument. The chip has a total sample count of 200, in 8 primes. If you have a LabChip GXII Touch HT instrument, you will need to use the Protein Clear HR LabChip Touch HT with the LabChip® GXII Touch Protein Clear™ HR assay instead.
Specifications
| Brand |
LabChip GXII
|
|---|---|
| Product Compatibility |
LabChip GXII Touch 24
|
| Unit Size |
1 unit
|
Configurations
Protein clear HR assay specifications
| Parameter | Specification |
|---|---|
| Sizing range | 14-250 kDa |
| Maximum sample concentration | 2000 ng/μL |
| Sizing resolution* | Resolution > 1.0 for VeriMAb reference standard |
| Sizing precision RSD (CV) | <2% |
| Relative migration time precision RSD (CV) | <2% |
| Percent purity reproducibility | <0.5% Main non-reduced IgG <5% all other peaks |
| Sensitivity (LOD) | 5 ng/μL (mAb, non-reduced main peak) |
| Linear concentration range | 10 – 1000 ng/ μL (mAb, non-reduced main peak) |
| Linearity (R^2) | >0.995 |
| Separation time per sample | 65 seconds |
| Maximum number of samples per calibration | 96 |
| Chip lifetime | 400 samples |
| Reagent kit primes | 10 |
| Minimum sample volume | 2 μL |
Resources
In this application note mAbs were evaluated using both the Protein Clear™ HR assay and an orthogonal method, the SCIEX® PA800...
Read the LabChip® GXII Touch™ protein characterization system product note to learn about an automated alternative to traditional...
Capillary electrophoresis (CE), more specifically CE-SDS, is becoming an increasingly popular and routinely used method for...
SDS, COAs, Manuals and more
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