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Don't lose your reads to highly expressed transcripts

If rRNA or globin transcripts are taking a big share of reads in your RNA-seq libraries, you are losing depth on the genes you actually care about. The NEXTFLEX™ Cas9-gRNA Depletion Enzymes remove rRNA or globin-derived fragments at the double-stranded DNA (dsDNA) stage, so you can reclaim sequencing capacity without changing your existing bulk or single cell RNA-seq workflow.
These modules offer:

  • Improved detection of rare transcripts
  • Affordable: Highly cost-competitive
  • Fast: Short one hour reaction time with only 5 minutes of hands-on time
  • Convenient: Easily fit into any library prep workflow
  • Flexible: Compatible with short and long-read sequencing
  • Automation-compatible - easily incorporated into manual or automated workflows

Use promo code NEXCAS9 to get 50% off on a 50 µL evaluation kit using the following catalog numbers:

Act now. Offer ends November 30, 2026


TERMS & CONDITIONS: Promotional offer is available for first time purchase of the NEXTFLEX Cas9-gRNA Depletion Enzyme. Promotional discount may not be combined with any other discount. Customer responsible for all applicable charges, taxes, shipping and other related expenses. We would appreciate your unbiased feedback about the kit after your testing.

Offer may not be applied to existing, pending or prior orders. Revvity reserves the right in its sole discretion to change the terms of or discontinue this promotion at any time without further notice. Revvity has the sole discretion to determine eligibility and reserves the right to request proof of eligibility, including age and residence. No cash or cash equivalent. No substitution. Void where prohibited or restricted by law. This promotion is governed by Massachusetts law and is subject to all applicable federal, state and local laws and regulations. All information submitted to Revvity in connection with this promotion will be treated in accordance with Revvity’s privacy policy, available at https://www.revvity.com/policies/website-privacy-notice. Offer is valid until November 30, 2026


For research use only. Not for use in diagnostic procedures.

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