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IVISense Renin 680 FAST Fluorscent Probe (ReninSense)

IVISense™ fluorescent imaging probes
IVISense Renin 680 FAST Fluorscent Probe (ReninSense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense™ fluorescent imaging probes

IVISense™ Renin 680 FAST (ReninSense™) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.

For research use only. Not for use in diagnostic procedures.

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Feature Specification
Unit Size 1 vial (10 doses)
Specificity Renin protease
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IVISense™ Renin 680 FAST (ReninSense™) is recognized and activated by rodent forms of renin in preclinical in vivo imaging models. IVISense Renin 680 FAST may be used to monitor abnormal Renin-Angiotensin System (RAS) function, progression of disease, and the efficacy of therapeutic treatment in disorders such as hypertension, cardiovascular disease, as well as some neurological diseases.

For research use only. Not for use in diagnostic procedures.

View product information
Product variant
Wave Length: 680 nm
Part #:
NEV11079
List price
USD 618.85
Your online price:
For research use only. Not for use in diagnostic procedures.
IVISense™ fluorescent imaging probes
IVISense Renin 680 FAST Fluorscent Probe (ReninSense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Renin 680 FAST Fluorscent Probe (ReninSense)
IVISense™ fluorescent imaging probes

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Product information

Overview

IVISense Renin 680 FAST™ is a member of a family of activatable fluorescent imaging probes comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology), that confers an improved pharmacokinetic profile with a broader range of early imaging timepoints. This architecture also offers higher target specific signal with reduced background.

IVISense Renin 680 FAST is a Renin activatable agent that is optically silent upon injection and produces fluorescent signal after cleavage by renin produced in the kidneys. The Renin-Angiotensin System (RAS) is the hormone system involved in regulating blood pressure and fluid balance in the body.

Specifications

Brand
IVISense
Fluorescent Agent Type
Enzyme activated
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Specificity
Renin protease
Storage Conditions
-30 to -16 °C
Therapeutic Area
Hypertension
Kidney function
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Resources

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Application Brief
Characterization of NIR fluorophores for their potential in non-specific tissue accumulation
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