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Thymidine, [Methyl-3H]-, Specific Activity: 6.7 Ci/mmol, 250µCi

Thymidine, tritiated on the methyl group. This product is supplied steri-packaged in an aqueous solution, and is typically used in DNA cell proliferation assays.

For research use only. Not for use in diagnostic procedures
Part Number: NET027250UC
Unit Size: 250 µCi
Part Number: NET027001MC
Unit Size: 1 mCi
Part Number: NET027005MC
Unit Size: 5 mCi
  • 250µCi quantity of [Methyl-3H]-Thymidine is available for your research. Application of [3H]Thymidine can be found in: carboxy-terminal PTH fragments stimulating incorporation in vascular endothelial cells, quantification of granulocyte-macrophage colony-stimulating factor (GM-CSF) hypersensitivity in juvenile myelomonocytic leukemia (JMML), influence of parasympathetic non-adrenergic, non-cholinergic mechanisms on uptake (rat) in response to mastication, measurement of dendritic cell induced T cell response by intracellular ATP levels and uptake in human immunology, etc. Special Information: If aqueous solutions of thymidine are stored frozen (-20°C), care should be taken to protect the material from U.V. light during the thawing process to prevent possible dimerization. When [methyl-3H]thymidine is incorporated into cellular DNA and undergoes radiolytic decomposition, [3H]5-hydroxymethyl-2''-deoxyuridine (HMdU) is formed.* The formation of HMdU through transmutation of [methyl-3H]thymidine occurs at the rate of B-decay, which is 0.017% per day. The transmutation product is not volatile. *References S. Apelgot and B. Ekert, J. Chem. Phys. 60, 505 (1963). K. Fink, R. E. Cline, and R. M. Fink, Anal. Chem., 35, 389 (1963). Specifications and Criteria for Biochemical Compounds, Third Edition (ISBN 0-309-01917-6), National Academy of Sciences - National Research Council, Washington, D.C. 1972. G. W. Teebor, K. Frenkel, and M. S. Goldstein, Proc. Natl. Acad. Sci. USA 81, 318 (1984). H. Tono, S.S. Cohen, J. Biol. Chem. 237, 1271 (1962). M. Nemer, J. Biol. Chem. 237, 143 (1962).

  • Molecular Weight
    242.2
    Application
    Molecular Biology
    Brand
    NEN Radiochemicals
    Detection Method
    Radiometric
    Label Position
    Specifically Labeled
    Radionuclide
    3H
    Radioisotope
    H-3
    Shipping Conditions
    Shipped Ambient
    Special Ordering Information
    This is a radioactive product - shipping address must have a license to receive radioactive materials.
    Unit Size
    250 µCi

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