Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
For research use only. Not for use in diagnostic procedures.
250µCi quantities of Scopolamine Methyl Chloride, [N-methyl-3H]-, are available for your research. Scopolamine is a natural product antagonist of muscarinic acetylcholine receptors, and is used to treat motion sickness and nausea.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET636:
Concentration |
1 mCi/ml
|
---|---|
Molecular Weight |
353.8
|
Application |
Drug Discovery & Development
|
---|---|
Brand |
NEN Radiochemicals
|
Buffer |
Ethanol
|
Detection Method |
Radiometric
|
Label Position |
Specifically Labeled
|
Packaging |
NENSure vial
|
Radioisotope |
3H
|
Receptor Type |
Acetylcholine (Muscarinic)
|
Shipping Conditions |
Shipped in Dry Ice
|
Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Storage Conditions |
-20°C
|
Therapeutic Area |
Cardiovascular
CNS & Neurologic
Gastrointestinal
|
Unit Size |
250 µCi
|
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