Skip to main content
Menu
US

Ro 15-1788, [N-Methyl-3H]-, 1 mCi

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Feature Specification
Concentration 1 mCi/ml
Label Position Specifically Labeled
Molecular Weight 303
Receptor Benzodiazepine
GABAA

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variants
Unit Size: 250 µCi
Part #:
NET757250UC
List Price
USD 3,857.00
Unit Size: 1 mCi
Part #:
NET757001MC
List Price
USD 8,792.00

Overview

1 mCi quantities of Ro 15-1788, [N-Methyl-3H]-, are available for research. Ro 15-1788 acts as a selective benzodiazepine antagonist. It is used to treat benzodiazepine overdoses and reverse anesthesia.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET757:

  1. Benke D, Cicin-Sain A, Mertens S, Mohler H. Immunochemical identification of the alpha 1- and alpha 3-subunits of the GABAA-receptor in rat brain. J Recept Res. 1991;11(1-4):407-24.
  2. Goeders, N., Kuhar, M.J. Benzodiazepine receptor binding invivo with [3H]-Ro 15-1788, Life Sciences, Volume 37, Issue 4, 1985, Pages 345-355.

Specifications

Concentration
1 mCi/ml
Molecular Weight
303
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Ethanol
Detection Modality
Radiometric
Label Position
Specifically Labeled
Packaging
NENSure vial
Radioisotope
3H
Receptor
Benzodiazepine
GABAA
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-80°C
Therapeutic Area
CNS & Neurologic
Unit Size
1 mCi

Resources

Are you looking for resources, click on the resource type to explore further.

1-2 of 2 Resources
Product Info Icon
Product Info
Calendar: NEN® Radiochemicals 2024 Fresh Lot
Flyer Icon
Flyer
NENSure: The safest packaging for radiochemicals
Scroll Icon