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IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)

IVISense™ fluorescent imaging probes
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense™ fluorescent imaging probes

IVISense™ Folate Receptor 680 fluorescence imaging probe (FolateRSense™) is highly specific and sensitive in its detection of Folate Receptor alpha (FRa).

Used with in vivo imaging systems such as Revvity's industry leading IVIS® platform, this targeted probe enables the non-invasive visualization and quantification of FR expression in highly metabolic cells such as tumor cells.

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Feature Specification
Unit Size 1 vial (10 doses)
Specificity Folate receptor
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IVISense™ Folate Receptor 680 fluorescence imaging probe (FolateRSense™) is highly specific and sensitive in its detection of Folate Receptor alpha (FRa).

Used with in vivo imaging systems such as Revvity's industry leading IVIS® platform, this targeted probe enables the non-invasive visualization and quantification of FR expression in highly metabolic cells such as tumor cells.

View product information
Product variant
Wave Length: 680 nm
Part #:
NEV10040
List price
USD 595.35
Your online price:
For research use only. Not for use in diagnostic procedures.
IVISense™ fluorescent imaging probes
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes

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Product information

Overview

Folate receptors are a family of cell surface receptors that bind the essential vitamin folic acid (folate, vitamin B9). These receptors are upregulated in highly metabolic cells and over-expression of FRA protein is associated with tumor growth, as uptake of folic acid is a necessary part of tumor metabolism.

Folate is essential for cellular metabolism and DNA synthesis, methylation, and repair. High metabolic cells such as proliferating cancer cells have increased demand for folate to maintain their accelerated DNA synthesis; thus overexpression of folate receptors (FRs) is a recognized biomarker of many tumors, though tumors can differ in their dependence on folate metabolism.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped Ambient
Specificity
Folate receptor
Storage Conditions
+2 to +8 °C
Therapeutic Area
Arthritis
Cardiovascular
Inflammation
Oncology
Pulmonary
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Resources

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Application Brief
Characterization of NIR fluorophores for their potential in non-specific tissue accumulation
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