Hemicholinium-3 (HC3; hemicholine) Diacetate Salt, tritiated on the methyl group. Hemicholinium-3 blocks reuptake of choline by the high-affinity choline transporter.
For research use only. Not for use in diagnostic procedures.
Feature | Specification |
---|---|
Concentration | 1 mCi/ml |
Label Position | Specifically Labeled |
Molecular Weight | 532.6 |
Receptor | Acetylcholine |
Hemicholinium-3 (HC3; hemicholine) Diacetate Salt, tritiated on the methyl group. Hemicholinium-3 blocks reuptake of choline by the high-affinity choline transporter.
For research use only. Not for use in diagnostic procedures.
Hemicholinium-3 is an inhibitor that blocks reuptake of choline by the high-affinity choline transporter. This transporter mediates drug delivery across the blood-brain barrier.
We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.
Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NET884:
Concentration |
1 mCi/ml
|
---|---|
Molecular Weight |
532.6
|
Application |
Drug Discovery & Development
|
---|---|
Brand |
NEN Radiochemicals
|
Buffer/Solvent |
Ethanol
|
Detection Modality |
Radiometric
|
Label Position |
Specifically Labeled
|
Packaging |
NENSure vial
|
Radioisotope |
3H
|
Receptor |
Acetylcholine
|
Shipping Conditions |
Shipped in Dry Ice
|
Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Storage Conditions |
-80°C
|
Therapeutic Area |
Cardiovascular
CNS & Neurologic
Gastrointestinal
|
Unit Size |
250 µCi
|
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