Skip to main content
Menu
US

DAMGO, [Tyrosyl-3,5-3H(N)]-, 250µCi (9.25MBq)

DAMGO, tritiated at the tyrosyl 3,5 poisition. DAMGO is a synthetic opioid analog with high specificity for the μ-opioid receptor.

For research use only. Not for use in diagnostic procedures

Part number: NET902250UC
List price: USD 3,101.00
Your price:
USD 3,101.00
USD 3,101.00 /each

Overview

DAMGO is a synthetic agonist with high selectivity for the mu-opioid receptor (MOR). These receptors are a group of GPCRs that are involved in analgesia, and are potential drug targets for drug addiction.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET902:

  1. Page, K., Besret, L., Jain, M. et al. Effects of systemic 3-nitropropionic acid-induced lesions of the dorsal striatum on cannabinoid and µ-opioid receptor binding in the basal ganglia. Exp Brain Res (2000) 130: 142.
  2. Jessica R. Gugusheff, Sung Eun Bae, Alexandra Rao, Iain J. Clarke, Lucilla Poston, Paul D. Taylor, Clive W. Coen, Beverly S. Muhlhausler, Sex and age-dependent effects of a maternal junk food diet on the mu-opioid receptor in rat offspring, In Behavioural Brain Research (2016) 301: 124-131.

Specifications

Molecular Weight
513.7
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Detection Method
Radiometric
Label Position
Nominally Labeled
Radionuclide
3H
Radioisotope
H-3
Receptor Type
Opioid
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area
CNS & Neurologic
Inflammation
Pain
Unit Size
250 µCi

Resources

1-1 of 1 Resources
Calendar Icon
Calendar
2024 Fresh Lot Calendar
SDS, COAs, Manuals and more Illuminator

SDS, COAs, Manuals and more

Are you looking for technical documents for this product. We have housed them in a dedicated section., click on the links below to explore.

Scroll Icon