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LH-RH, [125I]-[D-Trp6]-, 50µCi

Luteinizing Hormone Releasing Hormone (LHRH), labeled with 125I. LHRH binds LHRH receptors, and is a drug target for cancer therapy.

For research use only. Not for use in diagnostic procedures
Part Number: NEX365010UC
Unit Size: 10 µCi
Part Number: NEX365050UC
Unit Size: 50 µCi
  • 50 µCi Quantities of LH-RH, [125I]-[D-Trp6]- are available for your research.

    We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

    Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

    References for NEX365:

    1. Mehmanesh, H., Almeida, O.F., Nikolarakis, K.E., Herz, A. (1988), Hypothalamic LH-RH release after acute and chronic treatment with morphine studied in a combined in vivo/in vitro model. Brain Res, 451 (1-2): 69-76.
    2. Carelli, C., Ralamboranto, L., Audibert, F., Gaillard, J., Briquelet, N., Dray, F., Fafeur, V., Haour, F., Chedid, L. (1985), Immunological castration by a totally synthetic vaccine: modification of biological properties of LH-RH after conjugation to adjuvant-active muramyl peptide. Int J Immunopharmacol, 7 (2): 215-224.
  • Application
    Drug Discovery & Development
    Brand
    NEN Radiochemicals
    Detection Method
    Radiometric
    Fresh Lot Days
    Second Monday of each month
    Label Position
    Nominally Labeled
    Radionuclide
    125I
    Radioisotope
    I-125
    Receptor Type
    Gonadotropin-releasing hormone
    Shipping Conditions
    Shipped Ambient
    Special Ordering Information
    This is a radioactive product - shipping address must have a license to receive radioactive materials.
    Therapeutic Area
    Cancer
    Unit Size
    50 µCi

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Iodine-125 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Iodine-125. While we...