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CP 55940, [Side Chain-2,3,4-3H(N)]-, 25µCi (925kBq)

CP 55,940, tritiated on the side chain-2,3-4 position. CP 55,940 is a synthetic cannabinoid that acts as a full agonist at both cannabinoid CB1 and CB2 receptors, and can also upregulate serotonin 5-HT2A receptors.

For research use only. Not for use in diagnostic procedures
Part Number: NET1051025UC
Unit Size: 25 µCi
Part Number: NET1051250UC
Unit Size: 250 µCi
Part Number: NET1051001MC
Unit Size: 1 mCi
  • 25 µCi quantity of CP 55940, [Side Chain-2,3,4-3H(N)]-, is available for your research.

    CP 55,940 is a synthetic cannabinoid that mimics the effects of naturally occuring tetrahydrocannabinol (THC). It acts as a full agonist at cannabinoid receptors type 1 and 2. These GPCRs are potential drug targets for a variety of diseases, including epilepsy, cancer, obesity, and osteoporosis.

    We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

    Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

    References for NET1051:

    1. Chiang, Y.-C. and Chen, J.-C. (2007), The role of the cannabinoid type 1 receptor and down-stream cAMP/DARPP-32 signal in the nucleus accumbens of methamphetamine-sensitized rats. Journal of Neurochemistry, 103: 2505–2517.
    2. Gatch MB, Kozlenkov A, Huang RQ, Yang W, Nguyen JD, González-Maeso J, et al. (2013), The HIV antiretroviral drug efavirenz has LSD-like properties. Neuropsychopharmacology, 38: 2373–2384.
  • Molecular Weight
    376
    Application
    Drug Discovery & Development
    Brand
    NEN Radiochemicals
    Detection Method
    Radiometric
    Label Position
    Nominally Labeled
    Radionuclide
    3H
    Radioisotope
    H-3
    Receptor Type
    Cannabinoid
    Shipping Conditions
    Shipped in Dry Ice
    Special Ordering Information
    This is a radioactive product - shipping address must have a license to receive radioactive materials.
    Therapeutic Area
    Angiogenesis
    Cardiovascular
    CNS & Neurologic
    Gastrointestinal
    Inflammation
    Metabolic Disorders
    Pain
    Unit Size
    25 µCi

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