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Iodo-(-)-Cyanopindolol, [125I], 100µCi (3.7MBq)

Iodo-(-)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.

For research use only. Not for use in diagnostic procedures.

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Feature Specification
Fresh Lot Days First Monday of each month
Label Position Nominally Labeled
Molecular Weight 411
Receptor Adrenoceptors

Iodo-(-)-cyanopindolol, labeled with 125I. Cyanopindolol acts as an antagonist at β1 adrenergic receptors and serotonin 5-HT1A receptors.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variants
Unit Size: 100 µCi
Part #:
NEX189100UC
List Price
USD 2,044.00
Unit Size: 500 µCi
Part #:
NEX189500UC
List Price
USD 8,792.00

Overview

100 µCi Quantities of iodo-(±)-Cyanopindolol, [125I], are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX189:

  1. Houseknecht, K., Bauman, D., Carey, G., Mersmann, H., (1995), Effect of bovine somatotropin and food deprivation on β-adrenergic and A1 adenosine receptor binding in adipose tissue of lactating cows, Domestic Animal Endocrinology, 12 (4): 325-336.
  2. Mersmann, H., McNeel, R., Morkeberg, J., Shparber, A., Hachey, D., (1992), β-Adrenergic Receptor-Mediated Functions in Porcine Adipose Tissue Are Not Affected Differently by Saturated vs. Unsaturated Dietary Fats, The Journal of Nutrition, 122 (10): 1952–1959.

Specifications

Molecular Weight
411
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
1 propanaol : water : phenol (~50:50:1 2)
Detection Modality
Radiometric
Fresh Lot Days
First Monday of each month
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Adrenoceptors
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
4°C
Therapeutic Area
CNS & Neurologic
Unit Size
100 µCi

Resources

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Product Info
Calendar: NEN® Radiochemicals 2024 Fresh Lot
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Guide
Iodine-125 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Iodine-125. While we...

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NENSure: The safest packaging for radiochemicals
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