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GLP-1 (7-36), [125I]-, 50µCi (1.85MBq)

Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.

Feature Specification
Fresh Lot Days First Monday of each month
Label Position Nominally Labeled
Molecular Weight ~3298
Receptor Glucagon

Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.

Product variants
Unit Size: 10 µCi
Part #:
NEX308010UC
List price
USD 2,344.00
Your online price:
Unit Size: 50 µCi
Part #:
NEX308050UC
List price
USD 4,339.00
Your online price:
For research use only. Not for use in diagnostic procedures.

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Overview

50 µCi Quantities of GLP-1 (7-36), [125I]- are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX308:

  1. Wallrapp, C., Thoenes, E., Thürmer, F., Jork, A., Kassem, M., Geigle, P. (2013), Cell-based delivery of glucagon-like peptide-1 using encapsulated mesenchymal stem cells. J MIcroencapsul, 30 (4): 315-324.

Specifications

Molecular Weight
~3298
Specific Activity
2200 Ci/mmol (81.4 TBq/mmol)
CAS Number
107444-51-9
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
50 MM Sodium Acetate at pH4 with 50mm L-Ascorbic Acid, 50mm N-Acetylmethionine, 5% Sucrose and 0.25% BSA
Detection Modality
Radiometric
Fresh Lot Days
First Monday of each month
Label Position
Nominally Labeled
Molecular Formula
C149H226N40O45
Packaging
NENSure vial
Radioisotope
125I
Receptor
Glucagon
Shipping Information
Shipped on Dry Ice
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-20°C
Therapeutic Area
Gastrointestinal
Unit Size
50 µCi

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