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Whitepaper

Optimizing AAV manufacturing: a scalable harvest protocol

As demand for recombinant AAV (rAAV) vectors continues to rise, scalable and efficient manufacturing processes are essential for advancing gene therapy. Our latest White Paper evaluates a scalable harvest protocol across multiple AAV serotypes, comparing its impact on vector integrity, functionality, and yield against standard methods.

Key insights include:

  • Vector integrity & functionality assessment
  • Capsid recovery and yield efficiency
  • Empty/full capsid ratios and aggregation analysis

While initial yields were slightly lower, the study confirmed that vector quality remains uncompromised, making this a promising step toward cost-effective, large-scale AAV production.

For research use only. Not for use in diagnostic procedures.

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Optimizing AAV manufacturing: a scalable harvest protocol

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