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Application Note

HTRF assays address interaction complexes of various sizes and affinities

Protein-protein interaction formats are within range!

These two notes provide examples and data showing how you can use HTRF assays to study protein-protein interactions of widely varying sizes and affinities.

Partners could get as small as 3 kDa or as big as 150 kDa, and Kd could range from the picoMolar to the  microMolar, top-notch results are still at hand!

Get these to see how to perform such assays and interpret data to advance your research

Features:
  • Materials and methods for your experiments
  • Data processing and results analysis
  • Examples from R&D and scientific literature

For research use only. Not for use in diagnostic procedures.

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Application note
HTRF PPI reagents to address low to high affinity complexes
This application note demonstrated that HTRF PPI reagents are successfully used combining high detection performance, accurate modulators screening, and pharmacological characterization
Application note
HTRF probes all types of protein-protein interaction, from small to very large complexes
This application note demonstrates the suitability of HTRF® for PPI investigations whatever the size of the complexes studied.