Deeper insights in drug discovery with 3D phenotypic profiling

Cell painting has become a well-established technique for phenotypic screening with 2D cell cultures. However, with the progression to more biologically relevant preclinical models, an evolution of the workflow is required.

In this webinar, Dr. Martin Engel (Inventia Life Science) discusses the creation of advanced cellular models using the RASTRUM platform that can be used with the standard cell painting procedure. In addition, Dr. James Hutt (Revvity) describes how cell painting reveals deeper insights into cellular phenotypic responses.

Key topics:

• Reduction of assay complexity through the creation of advanced cellular models, optimized for phenotypic screening
• Use of automatically-generated 3D cancer cultures in the standard cell painting workflow with minimal modifications
• Identifying heterogeneity within cell populations
• Identifying where the “target of interest” is active in the cell.

For research use only. Not for use in diagnostic procedures.