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GSP Neonatal 17α-OH-progesterone kit
GSP Neonatal 17α-OH-progesterone kit
GSP Neonatal Kit
| Feature | Specification |
|---|---|
| Application | Newborn Screening |
Product variant
Unit Size: 1 kit
Part #:
3305-001U
For in vitro diagnostic use. This product is only available where licensed in accordance with law. Please contact your local representative for availability.
GSP Neonatal 17α-OH-progesterone kit
GSP Neonatal Kit
GSP Neonatal 17α-OH-progesterone kit
Product information
Overview
Congenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11a-hydroxylase deficiency. These types represent 95% of CAH cases and in both, the 17a-OH progesterone (17OHP), a precursor of cortisol, is increased. The determination of 17OHP is thus a useful screening method for 95% of all CAH cases.
GSP Neonatal 17a-OH-progesterone assay:
- Incubation time 3 h
- Sensitive, robust DELFIA chemistry for confidence in results
- All reagents are ready to use
- Contains reagents and plates for 1152 tests (12 plates)
The GSP Neonatal 17a-OH-progesterone assay is based on the competitive binding of europium-labeled 17OHP and 17OHP in the sample to 17OHP-specific antibodies. The fluorescence signal is inversely proportional to the analyte concentration in the sample.
All Revvity neonatal products may not be available in all countries.
Specifications
| Application |
Newborn Screening
|
|---|---|
| Brand |
GSP®
|
| Detection Modality |
Time-Resolved Fluorescence (TRF)
|
| Disorders |
Congenital Adrenal Hyperplasia (CAH)
|
| Instrument Compatibility |
GSP
|
| Quantity |
1152 tests
|
| Sample Type |
Dried blood spots
|
| Technology |
DELFIA
|
| Unit Size |
1 kit
|
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