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Application Note

Accelerate Parkinson's disease drug discovery with no-wash LRRK2 assays

Unlock the potential of HTRF™ LRRK2 immunoassays to support and advance Parkinson's disease drug discovery. This comprehensive application note provides valuable insights for rapid detection and characterization of LRRK2 targeting agents.

This application note features:

In-depth understanding of the role of LRRK2 in Parkinson's disease and its pathogenic mutations.
Detailed assay principles and formats for accurate measurement of phosphorylated LRRK2 and total protein levels.
Robust validation data showcasing the effectiveness of various LRRK2 kinase inhibitors and PROTAC degraders.
Practical recommendations for optimizing assay conditions and ensuring reliable results.

For research use only. Not for use in diagnostic procedures.

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Accelerate Parkinson's disease drug discovery with no-wash LRRK2 assays

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